Trivan Plus Special Precautions

Amlodipine and valsartan is considered a pregnancy Category medication. This means that it is probably not safe for use during pregnancy. Amlodipine and valsartan can increase the risk of birth defects and other severe problems.
Amlodipine and valsartan can lower the patient's blood pressure too much. Signs of low blood pressure include lightheadedness, dizziness, or fainting. Congestive heart failure, a recent heart attack, or surgery can increase the risk of low blood pressure.
If the patient has liver disease, the body may not metabolize amlodipine and valsartan as well as it should. Therefore, the patient may require extra monitoring by the healthcare provider and the patient may need to take a lower amlodipine and valsartan dosage.
Amlodipine and valsartan may decrease kidney function, which is not a problem for most people. However, if the patient has kidney disease or heart failure, this may cause problems.
If the patient has severe coronary artery disease, there is a low possibility that taking amlodipine and valsartan may increase the chances of worsening chest pain or heart attack.
Amlodipine and valsartan can interact with a number of other medications. It is not known if amlodipine and valsartan passes through breast milk. Therefore, if the patient is breastfeeding or plan to start, discuss this with the healthcare provider prior to taking the drug.